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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '5cf5c512bc027ff408e4063529f91b1003dcfbbdaf7cb9275e99f37fa5c235bd' 
  AND token = '2cOGrzmsANzDw7psNGnOfO54HZlmoLrw+tWpHXBGXHc=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00029

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}