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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '9d04eb1ce73192ff19f48b4d570f5f9c01a4fa57a11bcf67b883c9a3730d7e03' 
  AND token = 'IpFzWzP16EnFUgYazrhwhPE6UjCaN5gKleKnD1kxf/8=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00026

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}