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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '16d5c9720587f47b633e9110a5f5525592c094e839a99cc3933a23b03c46263a' 
  AND token = 't1q0a9MJy36iDObucB36UXk3XNN0mB7JsOHIYLbzZh8=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00026

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}