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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'dc505216e45653a2211b0390c26947a2890805b47b5442be700ec3ffdfdb2abf' 
  AND token = '8HnvQ8EIyNFbxuMIDgV8G04+TYtA3SefX0nbvcqgC5U=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00033

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}