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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '271950cca7e1e48b446b44954ce883673cc5b76732fc8ebec7dd3fa257f90bbb' 
  AND token = 'qBhtywPVKRWFnf4T1I996EAwEWpkCUWO5hcsSXYc3oY=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00048

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}