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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'bed3d1cd1ceee1120a1ba204516a009297837bc0fa7f7c8d09c1a558d974d4ea' 
  AND token = 'TaGNlRFYVXm8HpLhcJCbLvl+GopYCNJo98W0soU6Tng=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00049

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}