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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '495bd148bf1f58a02795e94d00dec1797ad060edabc318523153a77bc3cfeed4' 
  AND token = 'CS3aAsHzoLE28ti227DQl3UaROK4hYerv0MiWHBFdGE=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00024

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}