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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'e6394ea5239bc227fe409331e0d374eb0e9fc0cd2d2bd382b6a5ec068609e048' 
  AND token = 'eQprE1W5lT+mOx2o9ErOM0LOIdkwOxDlAwqZMIwxuNQ=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00027

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}