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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'e546415af93253557cb4ece3dce0121045cb8a6495de45ea199a036c704fff6a' 
  AND token = 'QU/u9OgfegD2xoLlngsn91yC7Zi1K6Wezjn4AzNO0no=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00029

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}