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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '6f95b94f8abed62516ff3393b9a1c8a1e34cc4a2c0a06176dc78876f045b6260' 
  AND token = 'yp01LbDaady8re2ihhMeHPbcw5HiscBLpDBVdSEI+Hk=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00019

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}