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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '5953a24256a4f87b383305c81b1bfa405e72ffed89b479a7cd3bde3b5ae10baf' 
  AND token = 'zAS7A6cbw1pZabhr/v7s4MXcCafQ0dH+prWlvZlLnvQ=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00022

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}