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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '0e54b26698fc01f8a5fb5c3ca93e2e9e1cfdc84f38facac06371fc9ecad3bc22' 
  AND token = 'et3fks9d4nCSaf8K1/2ohwOPxsW9M4nv7KW/Q/1HV6Q=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}