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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '1015e2ecb74a51299b6c657eb6d935ddcb733a9d18a0ace49332e7a0cfc594b9' 
  AND token = 'vVW7fYaDkwsk5a5pSYf0lAtgCSCp4vkU0BwgBKHdcd4=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00023

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}