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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '2ee0288d8aced19083855c7c1d702066ee3f6736dd3c5f0715f054d049676b3a' 
  AND token = '8hoceUaD7AZ3JR+6fYkzt2d3qk9NhOSRNYjZGS5lS1M=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00033

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}