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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '581a7ef89659edf2d32a818933716a19d56332469d081cc7442fadaa98067350' 
  AND token = 'kcFZzQ5FA9FMbUYCz6XxBPtX25yd5ROG+Zw2pFMwnV0=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00028

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}