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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '4c9e71a5a7e3e8be7f60c4f9beb94052b6db44c8dd8b9b612830302db72f969a' 
  AND token = '53JPcrt77k8MAI5M3AT7ouXoizLVmZhpPKZbP9CqEcA=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}