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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '0eb337877b96c79cbe9f35e2825c110b714bbbccdf22b5a755b157a1635fb10d' 
  AND token = 'CDg6wOzszahSLcfDjC1X6Uc57Kz8ReNJBHi9TG1NgiU=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00021

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}