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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'a065d5f53f9b86995c61a312bb44d2669e3eb6bc669abecfd068df22ab2779bf' 
  AND token = 'JQwQDhT2PMp5dk0Xugy2dKx3bL7ebutX0mkd1kzywbc=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00023

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}