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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '4765ee9260ca91d993fbe5a0e2e7f4747f7203eb81878c76f8435d3033d222ce' 
  AND token = 'NlvpB+P8ebyllI5MMsBqF3+SO3OLA01USlWWyfTCdWk=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}