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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'fb274e8cd08f021dd73697906f4ff690692f912c06b269ea9dd00bdd3e0a08b2' 
  AND token = 'VvNjq7b4YkkFmLqGnTsYZaql+6L2jBMEdTiOVcnV0nE=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00030

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}