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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '849d91a1612f5bd3b8ae71dd6e9082a876a9f8f28182cc35f362044bb777f934' 
  AND token = 'P09ZdM87wmRQ5+fDcpy1Mz2I5ANuO7jbqb9iNg51IX0=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00021

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}