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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'acf88f3db61c3a5debc61e1656f1c732f8d9e02faf58915f17eea150e4a60bcf' 
  AND token = '+Fw3DjBEaPQoQyvN4PCcxY121T8DUi982kM/spEMU08=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00039

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}