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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'aa8422eeb215c030163f8df90429df0d70f2fa1f99262ffaac1304f1d66753b5' 
  AND token = '8PqS+4SA7ezgOTFdWPtxutMflL9tf4c4aTgT9d+Uk1w=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00044

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}