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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '4f7a3fa1edf851de52763d61cf5f012b1b2c30cc007b99c4f27740eaa188b56f' 
  AND token = 'vf0XbdvGrORnyX1UCOzHOrxNLgUoOymv0drgcm/Kzco=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}