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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'c759ebdd78c2f4eec4a74ae8d88fca8b0afb635c917e52212b20cb3b0e9c9f56' 
  AND token = 'NHz0CdADBuPQuDykgdi3XgEBTBdSPscZ49wNGS2Bc+s=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00026

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}