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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '594ee77d3ecca1b72a2c3edac74c2394f6b9ff12d00b8eba53fcd348332bda2d' 
  AND token = '7wpT64QnCTAb0Or+qYh9AMDbfyTPJTd2R2bX75LPY+Q=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}