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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '5ff3bfc0690d12e8c22750d01eacf45e29267c9d04b864bbdee0e8492a9c2845' 
  AND token = 'WPc/lKfQQLMilQMVG/r/lm7Y+FyNs4FPtmn4/zaD9Q8=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00031

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}