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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '18387a3d2df93100c0e4888dbb2f8a253803821e5d38e661ab648b4fbf9f23c2' 
  AND token = 'LBxpQLJmz2pFl2KnP8gYDLMIuyZzn5vzxh1CH0N4lmk=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00033

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}