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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '024ada5ed0847af96d65e70b9752975bfcbeca55af498b15640af30632908396' 
  AND token = 'ZybyPEo/x2zuVy25RDSt8oiy5XmDyrM7NMWdfI5CBPE=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00049

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}