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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '88dc609a71f2a89bba2f13460c598f6dc38f82bdc22088c37a62134087be0f42' 
  AND token = 'PtL6coRzu6Chfu8PBI0XAkC9XvLa6Ch11eNWdHtga4M=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00022

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}