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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'f8894162135239f85b8614bcdebd398a37aad799265b44f0d6c2b143ff44982f' 
  AND token = 'u1mw8XoHahxn1767+OsWwdtr/BZAiNoa0WjyLqCn7jk=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00019

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}