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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '00ceb60eda2a7cee5159708d58675fbc08108c90f7fdf7e2c9d1e187dc79e2f5' 
  AND token = '384SW1F+vU8AJ5mywebOKz3vry7qkfoVTrief1+c53Q=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00024

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}