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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'ed07e2df34c20ad4d754a63e626e7cdd486b4289892968b9efff2db0acb2300d' 
  AND token = 'vF7qyMH+YfsZCLYrmyf0XysAP3ATNN9ziuc/HZck6hQ=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00027

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}