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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '1242a57fd6512e9a416559ab7699c71242cdee0fe4695003a9838dc4eb2f21c6' 
  AND token = 'wR/ryV+aeERyBayz68AkJWehTWooK6ShFpzDHP8BQ8Q=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00049

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}