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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '9723642025725cb8d7063b71d9d94466cfe23be54278f2f2e898d97e304cfcaf' 
  AND token = 'NZCxJ4U+gpE1DXk3v3ed+4kiG9gj4ReoJf07c1XU6s4=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}