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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '1343d27a530f92f77cd4abd644ae0a805e6dde835c33522a8ed222a21f2e55a8' 
  AND token = 'uTWYSQPOpdGajIJRSd7i97slYTIJVKEP5onK1wOqDZw=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00021

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}