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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '8074c1290a1183f761750df03fae72e21bcf38fec6646e83c06e4e1fa6d75eb4' 
  AND token = 'HltybQQhaWPKRil5vchGWRz23M6bSTAN5gNdCznkk1Q=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00027

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}