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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '50c852b3bcf93b6320181887dd190105e11d8e77f9f8de7b9ab76c84bd13ee44' 
  AND token = 'NGg1NwMkjQNkOVb4XR0Sz5jCP2kF+pZ+BA181f+i93w=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00027

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}