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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'e8260c5974d8677efe5cb61ef9572901e3c5a01e0801960de29bb5f2647488f8' 
  AND token = 'WTQNGC+ZeRF5xqi66z8Qsy4Y3L3oFdBajqwyI76SuYA=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00023

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}