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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '0c15dabb90f85d625acc276a77cb3e91bf54797f3ff2cb0d716e6fbde88e244f' 
  AND token = '254rvtlm+M3o/Csdvrt4nQSoVCzHdAjVRKT1lRLmnRU=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00021

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}