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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '0f3c3833b7de9a09e3602a595baf704d94be2fadf3333d0d494a4f1345f2da8f' 
  AND token = '6BAwJVrdJkuYJ5rc+eDew7rkG5aTT6nOurn8+Yii944=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00020

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}