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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '4ece8781718965396947cd683c638b1e96ef4ae384b1af6794ab57d07e67c4d0' 
  AND token = 'y+a/cEs0Avgm6eAhQMdFQ651/mJVz7dbY63YnD2H9OA=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}