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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '5c6228fa83b4381371a973783c7bae7ef89a7f97fa87251df6b178f19e78e5bc' 
  AND token = 'Vz26H+2HR11usa7kINjVbJpSEjaAJeSGCgnP9yRRFFw=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00024

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}