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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '24c44b196d75eacc4216b8cf53a24da2103549f0e7fa2cf67e87a04dda1a1987' 
  AND token = 'dER8ma4VYBBKCHkK+KjmPJWdLL3jf+JgXzbNCA9ekR4=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00036

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}