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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'fd428b92a98c0c0dec44830f50deeef48a4a1c16bff4f281a2b383e9f99098be' 
  AND token = 'SoCFcSEiAP98s/QWcXOlW9IKf1v3SQIs2IEUk3dqoPo=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}