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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '74adb145b25e028017aa153afa8992fbb392490a3196b2bbac041d464b02afb2' 
  AND token = '6mRKvnStfE3s8MS2w1dyhJ3SWEbAMjOyklABgk0f3a0=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00032

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}