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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'cf72736b634f93b4b9f3b5343f1dfc88c4789a080471b78eadb08520c39a71bd' 
  AND token = 'Mp/Pvxu9lgX2R3HOeEbk3JA8PPxF5ZsrO/b0Re0JzH8=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00022

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}