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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '3d4badadec2de95fa239b3f5f52c3e4f6670b18f565027ecc3507dc2326f6c7d' 
  AND token = 'HYdXgx+T+EPzEXZxGMSxaDqf3eN4jwStx26K6NL55qI=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00024

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}