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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '11e99a3990c7fefc58addb2311b3273787039a4a681ff42725af3a998e82c9f8' 
  AND token = 'uDtRJXcCp1Jw1qSPpJ17I+UbC6yP7G0ff1v3ft35lZM=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00020

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}