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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '4611906ac8fe8d4d5141967863ece655a6e961d2a9d05d2fedce6012c06e6535' 
  AND token = 'FqSJ9aOK6V5AbT4oMNouQ9Xmzc4YT+ZNK8RtxH9cxPY=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}